Return to Main Page

MAIN RESEARCH PROJECTS, COLLABORATORS, AND FUNDING SOURCES

Determination of structures of the O-specific polysaccharides (O-antigens) for classification of Proteus, Providencia, Yersinia, Photorhabdus, and some new genera of enterobacteria
In cooperation with

State Research Center for Applied Microbiology, Obolensk, Serphukhov District, Moscow Region, Russia

Institute of Microbiology and Immunology, University of Lodz, Lodz, Poland

D.K. Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kiev, Ukraine

Supported by

Russian Foundation for Basic Research (RFBR), 1996-2011

Characterization of the O-antigen structures and gene clusters for elucidation of the gene functions and the evolutionary history of the O-antigen gene clusters of Shigella, Escherichia coli, Salmonella, and Cronobacter
In cooperation with

TEDA College, Nankai University, TEDA, Tianjin, China

Supported by

Russian Foundation for Basic Research (RFBR), 2004-2012

Determination of lipopolysaccharide structures for elucidation of its relationship to the ability of the bacteria to activate the innate immune system
In cooperation with

Engelhardt Instiute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia

Department of Biotechnology, Alagappa University, Karaikudi, India

Supported by

Russian Foundation for Basic Research (RFBR), 2010-2012

Studies of polysaccharide antigens of probiotic microorganisms bifidobacteria and lactobacteria
In cooperation with

Institute of Microbiology, National Academy of Sciences of Belarus, Minsk, Belarus

Supported by

Russian Foundation for Basic Research (RFBR), 2008-2011

Elaboration, creation and maintenance of the open-access Bacterial Carbohydrate Structure Database

Supported by

International Science and Technology Center (ISTC) and U.S. Defence Threat Reduction Agency (ISTC partner), 2004-2005

Russian Foundation for Basic Research (RFBR), 2005-2007

Isolation and characterization of bacterial carbohydrates for construction of pathogen glycoarray
In cooperation with

Consortium for Functional Glycomics and The Scripps Research Institute, USA

Supported by

National Institute of Health (USA), 2006-2008

MAIN PAST PROJECTS

Determination of structures of the O-specific polysaccharides (O-antigens) for classification of enterobacteria Citrobacter, Hafnia, and Edwardsiella
In cooperation with

I.I. Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia

L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland

Supported by

Russain Academy of Sciences (RAS)

International Science Foundation (ISF), 1994-1995

Russian Foundation for Basic Research (RFBR), 1996-2007

Lipopolysaccharide (endotoxin) of the Legionnaire's disease bacterium Legionella pneumophila. Identification of new higher sugars (nonulosonic acids), determination of the chemical structure and epitope specificity
In cooperation with

Research Center Borstel, Center for Medicine and Biosciences, Borstel, Germany

Institute for Medical Microbiology and Hygiene, Medical Faculty, Technical University, Dresden, Germany

Supported by

Deutscheforschungsgemeinschaft (DFG), 1996-2001

Russian Foundation for Basic Research (RFBR), 2000-2002

Studies of the lipopolysaccharide of the gastric bacterium Helicobacter pylori
In cooperation with

Karolinska Institute, Clinical Research Center, Huddinge University Hospital, Huddinge, Sweden

Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden

Department of Microbiology, National University of Ireland, Galway, Ireland

Supported by

Royal Swedish Academy of Sciences, 1997-2000

International Association for the Promotion of Co-operation with Scientists from the New Independent States of the Former Soviet Union (INTAS), 1999-2002

Structural and functional aspects of the lipopolysaccharide of Pseudomonas aeruginosa
In cooperation with

Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA

Research Center Borstel, Center for Medicine and Biosciences, Borstel, Germany

Supported by

U.S. Civilian Research and Development Foundation, 1997-2001

Deutscheforschungsgemeinschaft (DFG), 2002-2004

Russian Foundation for Basic Research (RFBR), 2002-2004

Determination of structure of the lipopolysaccharides from different pathovars for classification of the phytopathogenic bacteria Xanthomonas campestris, Pseudomonas syringae and related spieces
In cooperation with

D.K. Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kiev, Ukraine

Institute for Plant Pathology and Plant Defence, Georg August University, Goettingen, Germany

Supported by

International Association for the Promotion of Co-operation with Scientists from the New Independent States of the Former Soviet Union (INTAS), 1997-2001

Russian Foundation for Basic Research (RFBR), 2002-2004

The role of the lipopolysaccharide structure in the resistance of the plague bacterium Yersinia pestis to antimicrobial cationic peptides and complement-mediated serum killing
In cooperation with

State Research Center for Applied Microbiology, Obolensk, Serphukhov District, Moscow Region, Russia

Research Center Borstel, Center for Medicine and Biosciences, Borstel, Germany

Supported by

International Science and Technology Center (ISTC) and U.S. Defence Threat Reduction Agency (ISTC partner), 2001-2005

Russian Foundation for Basic Research (RFBR), 2006-2007

All projects are performed in collaboration with the NMR Center
of the N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Return to Main Page